Sirturo 100mg Tablet
3 posology the recommended dosage of sirturois shown in the table below.
Sirturo 100mg tablet. Sirturo prescription and dosage sizes information for physicians and healthcare professionals. 400 mg 4 tablets of 100 mg once daily weeks 3 24. Sirturo is the first anti tb drug to interfere with bacterial energy metabolism. In the subset of patients with culture positive pulmonary mdr tb at baseline treatment with bedaquiline resulted in conversion to a negative culture in 100 3 3 patients at week 24.
400mg 4tablets of 100mg once. 2 6 see full prescribing information for the different methods of. Today s decision marks the first regulatory approval for the pediatric formulation of sirturo and is a key component of johnson johnson s global pediatric research and development r d program for the medicine. In the subset of patients with culture positive pulmonary mdr tb at baseline treatment with bedaquiline resulted in conversion to a negative culture in 75 0 6 8 patients at week 24.
The new 20 mg tablet can be administered with water for patients who are able to swallow the intact tablet and taken with food. Sirturo was administered as 200 mg once daily for the first 2 weeks and 100 mg 3 times week for the following 22 weeks using the 20 mg tablet. Reserve sirturo for use when an effective treatment regimen cannot otherwise be provided. 2 3 recommended dosage in pediatric patients 5 years and older and weighing at least 15 kg is based on body weight.
Only use sirturo in combination with at least 3 other drugs to which the. Get contact details and address id. Adolescents 12 years to less than 18 years of age and weighing at least 30 kg. Sirturo specifically inhibits mycobacterial atp adenosine 5 triphosphate synthase by binding to subunit c of the enzyme that is essential for the generation of energy in.
Sirturo was administered as 400 mg once daily for the first 2 weeks and 200 mg 3 times week for the following 22 weeks using the 100 mg tablet. Administer sirturo bedaquiline by directly observed therapy dot. Sirturo tablets should only be administered as part of a pulmonary multi drug resistant tuberculosis mdr tb regimen. 200 mg 2 tablets of 100 mg three times per week with at least 48 hours between doses.
Recommended dosage of sirturo. Of the 100 mg tablets or 10 of the 20 mg tablets 3 times per week with at least 48 hours between doses for 22 weeks. Get best price and read about company. Pharmacology adverse reactions warnings and side effects.
2 4 take sirturo tablets with food. Hetero drugs laboratories offering sirturo 100mg tablet ट बल ट स in vijayawada andhra pradesh.